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Special Emphasis Grants

For multidisciplinary, outcome-driven initiatives. Target outcomes should be based on restoration of neurological function, clinically relevant and of high priority to patients with spinal cord injury translating neurological plasticty.

New International Call - Healthcare innovations that could have a significant impact on bladder, bowel and sexual function
Description
The aim of the call is to support high-quality clinical research that develops and tests innovative ways to recover bladder, bowel or sexual function after spinal cord injury.
Call opens: 3rd April 2019
Call closes: 8th May 2019
Type of research: this call invites clinical research proposals/human proof-of-concept studies
Level of funding
Up to £250,000
You should request a level and duration of funding that is justifiable for your proposed activities.
Duration of funding
Usually between 24 -36 months
Any application is expected to have direct relevance to the fields of research discussed in the following published articles on the ISRT Research Strategy, copies are available: Adams et al. International Spinal Research Trust Research Strategy: a discussion document. Spinal Cord (2007) 45: 2-14.
Applications will be assessed competitively on the quality and relevance of the proposed research project.

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Strategy Awards

Basic science research grants usually three years in duration. These grants are available to international researchers. Strategy grants form our basic science programme and are normally awarded following an internationally-advertised competitive call for proposals based on themes identified by our Scientific Advisory Committee with reference to our research strategy discussion document. Calls for project proposals are advertised in published academic journals and through email alerts to researchers on our database. Project grants are generally for the support of a postdoctoral researcher to undertake the approved research plan over a period of up to three years, plus necessary consumables, travel or technical assistance. Support will also be considered for equipment if essential to the project.

Nathalie Rose Barr PhD Studentship

Available to principle investigators in UK research institutions, these three and a half year awards include a highly competitive stipend and consumables budget. These calls are not usually themed. The awards are aimed at encouraging the development of talented, highly-motivated young scientists in the field of spinal cord repair, in both clinical and basic science research environments. Calls for project proposals are advertised through email alerts to researchers on our database. The successful project supervisor is responsible for recruiting a suitable post graduate candidate. The PhD degree must be awarded from a UK university and a high priority is given to collaborative proposals between more than one laboratory or institution. Support includes university fees, a stipend in line with that offered by the Wellcome Trust, plus funds for consumables, travel costs and IT equipment. Typically, the PhD student is recruited to a team that is already established in the field of spinal cord injury research, where they will receive an excellent quality of training and support. As well as obligations within their own institution, all students are encouraged to attend and present their data at research conferences and to attend our annual Network Meeting.

Translational Award

Two year grants focused on translational activities aimed at addressing scientific and technical hurdles on the critical path to the clinic. These grants are not expected to be rich in new hypothesis.

Grants will be awarded to support the translation from the laboratory into the clinic of promising new treatments for spinal cord injury. Candidate treatments should already have demonstrated efficacy in a peer-reviewed publication in at least one in vivo spinal injury model, and should involve a clinically-feasible delivery procedure.
Funding is designed to bring promising treatments to a stage that they are ready for first-in-man studies, and will provide support for pre-clinical studies of the following example types: dose-response, toxicity and studies of the optimum therapeutic windows; optimisation of delivery methods; assessment in additional spinal injury models. Support for phase I clinical trials and clinical feasibility trails will also be considered. Funding through this scheme will not be available for projects where the primary aim(s) are to examine mechanisms of action, test novel therapeutic concepts or establish proof of principle. Milestones that are demonstrably on the critical path to the clinic are essential and will have a strong bearing on the success of the application.

Applicants will be expected to have considered possible primary and secondary clinical outcomes and the target patient cohort.

Solomons' Award

The Solomons' award is to help endorse quality experimental medicine, translational and reverse translational research in the UK within the field of spinal cord injury. The purpose of the award is to support the development of an early career clinical researcher with either a science or medical training background. The call is initially open to applicants from clinical units and allied research institutions that have an evident traumatic spinal cord injury case mix or demonstrable interest in SCI clinical research. The award is for up to £10,000 which may be made to a single recipient or may be split between two or more if felt warranted. A central theme is to encourage innovation, collaboration and research activity amongst early career researchers. In particular, we would welcome activity that helps bridge the basic science/clinical divide.

Our Solomons' awards are ongoing and open for applications.

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